Recent Autoimmune System News from Science Daily:

 

• Genetic test can diagnose certain immune system disorders
• Haywire T cells attack protein in ‘bad’ cholesterol
• Scientists smash lethal bacteria that acts like a hammer
• Killer T vs. memory — DNA isn’t destiny for T cells
• Uncovering new details of the brain’s first line of defense
• Dietary cholesterol worsens inflammation, sickness in mice with influenza
• ‘Sting’ protein’s efforts to clean up brain cell damage may speed Parkinson’s disease progress
• Type-I interferon stops immune system ‘going rogue’ during viral infections
• Friendly fungi announce themselves to their hosts
• Dynamics of adaptive immunity in tuberculosis uncovered
• ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis
• Biomaterial improves islet transplants for treatment of type 1 diabetes
• Early study finds new lymphoma drug effective
• Antibiotics can lead to fungal infection because of disruption to the gut’s immune system
• Solid tumors use a type of T cell as a shield against immune attack
• Immune cell characteristics mapped across multiple tissues, from early life to adulthood
• Study finds nanomedicine targeting lymph nodes key to triple negative breast cancer treatment
• How a leaky gut leads to inflamed lungs
• A fuzzy response from memory B cells can protect against mutant viruses
• Chagas disease: Hybrid strains make insidious parasite more dangerous
• Stopping lung damage before it turns deadly
• T cell behavior determines which tumors respond to treatment
• Targeting interleukin-6 could help relieve immunotherapy side effects
• Model finds COVID-19 deaths among elderly may be due to genetic limit on cell division
• Revealing the individual immune cells inside the plaque that causes life-threatening heart attacks
• Patient-derived micro-organospheres enable cutting-edge precision oncology
• Why do some people get sicker than others from COVID?
• Breaking the shield that protects pancreatic cancer from immunotherapy
• Vaccines induce multiple immune system mechanisms to protect against severe COVID-19 illness
• New discovery to improve malaria elimination strategies
• Stem cell therapy protects against the side effects of cancer drugs
• Investigating cancer drug toxicity leads to a critical discovery
• Fecal transplants reverse hallmarks of aging
• A better understanding of HIV-1 latency
• Study finds healthy-appearing lupus skin predisposed to flares, rashes
• ‘Resetting’ the injured brain offers clues for concussion treatment
• COVID-19 vaccine technique shows promise for heart disease
• Genetic links revealed between severe COVID-19 and other diseases
• CAR T drives acute myeloid leukemia into submission in pre-clinical studies
• New details behind the body’s response to tuberculosis could lead to a more effective vaccine
• Findings open way for personalized MS treatment
• How one inflammatory disorder exacerbates another
• A new treatment reduces inflammation in multiple sclerosis mice models
• Skin bacteria may boost immune response of mice vaccinated with smallpox vaccine, study shows
• Fungal meningitis spreads by blocking and bursting blood vessels
• Scientists identify potential new ‘soldier’ for cancer immunotherapy
• Weapon against tumors, boost for the immune system
• A new pathway to shrink cancerous tumors through body’s immune cells
• How air pollution alters lung tissue, increasing cancer susceptibility
• Researchers create 3D model for rare neuromuscular disorders, setting stage for clinical trial

Autoimmune Disease News

• New approach may lead to better diagnostic techniques for autoimmune disorders
• New Oral Drug Found to Reduce Relapses in Multiple Sclerosis Patients.  A new oral drug–teriflunomide–has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. ScienceDaily (Oct. 7, 2011)
• New oral drug found to reduce relapses in multiple sclerosis patients. A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. Science Daily (Oct 6, 2011)
• Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases. Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. Cleveland Clinic. (Oct. 7, 2011)
• Autoimmune diseases a growing problem, Johns Hopkins expert says. Autoimmune diseases are a large and growing problem, particularly in the Caribbean and the United States, says Dr. Noel Rose, director, Center for Autoimmune Disease Research at John Hopkins University, who presented on Autoimmune Disease: The Common Thread, during the Caribbean Autoimmune Diseases Summit 2011. Trinidad Guardian. (Oct. 4, 2011)
• New Research Could Extend Life of Arthritic Joints. A medication already approved to build bone mass in patients with osteoporosis–human parathyroid hormone (brand name: Forteo)–also builds cartilage around joints and could potentially be re-purposed to treat millions of people suffering from arthritis, according to orthopaedic research at the University of Rochester Medical Center. ScienceDaily (Sep. 21, 2011)
• Components That Keep Immune System in Check Identified.  Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body’s own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.  Now, researchers at the University of North Carolina at Chapel Hill have revealed the genetic underpinnings of the cells that can prevent the immune response from turning cannibalistic. Their finding lends insight into these key cells, which are currently being tested as treatments for autoimmune diseases such as type I diabetes, arthritis and lupus. ScienceDaily (Sep. 19, 2011)
• Blocking Inflammation Could Lead to Tailored Medical Treatments.  Researchers at the University of Calgary have discovered a new class of molecules that can inhibit   inflammation in the body – a key feature in autoimmune disease. Current anti-inflammatory drugs block all inflammation in the body. However, these newly discovered molecules may offer a more tailored course of treatment for some diseases, for example to help people suffering from inflammatory diseases such as Inflammatory Bowel Disease (IBD). ScienceDaily (Sep. 19, 2011)
• Starving inflammatory immune cells slows damage caused by multiple sclerosis, study finds.  Researchers report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis (MS).  Science Daily. (Sep 1,  2011)
• University of Miami Researchers Target Inflammatory and Autoimmune Diseases.  New research shows that activating a specific integrin—one of the receptors that mediate attachment between a cell and surrounding tissue and play a role in cell signaling—could lead to more therapies for fighting inflammatory and autoimmune diseases that afflict millions of people worldwide–Miller School of Medicine (Sept. 12, 2011)
• New Anti-Inflammatory Agents Silence Overactive Immune Response; offer  a promising new approach to treat inflammatory auto-immune disorders such as lupus and multiple sclerosis–Science Daily (Aug. 16, 2011)
• Three artists Shine Celebrity Spotlight on Autoimmune Disease Family Ties. Autoimmune disease often runs in families. Three celebrities recently announced their own fight with autoimmune disease and the family connections. American Autoimmune Related Diseases Association (AARDA). (July 28, 2100)
• Anti-malaria drug chloroquine finding may lead to treatments for arthritis, cancer and other diseases. In a new study, scientists demonstrate on the molecular level how the anti-malaria drug chloroquine (widely used to control inflammation in autoimmune diseases such as APS)  represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis and certain cancers – Science Daily (July 18, 2011)

• Newly Discovered B Cells Suggest Why Women Suffer More Autoimmune Disease  – National Jewish Hospital (July 1, 2011)

• Shingles can increase risk of triggering multiple sclerosis, study finds – Los Angeles Times (June 9, 2011)

• New approach for identifying autoimmune diseases developed by Harvard Researchers – Science Daily (June 2, 2011)

• Cardiac Arrhythmia Tied to Autoimmune Diseases – Doctors Lounge (May 6, 2011)

• Lupus complication rates soar in young people – Medical News Today (March 29, 2011)