Recent Autoimmune System News from Science Daily:

 

• Brain-repair discovery could lead to new epilepsy treatments
• New insights into immune responses to malaria
• ‘Missing self’ contributes to organ rejection after transplantation
• ‘Good cholesterol’ may protect liver
• Cell-analysis technique could combat tuberculosis
• Structural biology provides long-sought solution to innate immunity puzzle
• Llama ‘nanobodies’ could hold key to preventing deadly post-transplant infection
• Researchers find immune component to rare neurodegenerative disease
• Study links vaccine immune response to age
• Blocking how the malaria parasite suppresses the immune response
• Unleashing Treg cells may lead to treatments for multiple sclerosis
• SARS-CoV-2 spike mutation L452R evades human immune response and enhances infectivity, researchers find
• No IgA leads to intestinal inflammation in mice
• Novel autoantibody adds fuel to COVID-19 ‘firestorm’ of inflammation, blood clots
• Study shows why second dose of COVID-19 vaccine shouldn’t be skipped
• Simple compound to control complex gut microbes
• When mad AIOLOS drags IKAROS down: A novel pathogenic mechanism
• New theory suggests blood immune and clotting components could contribute to psychosis
• New UK study reveals extent of brain complications in children hospitalized with COVID-19
• Human cells harness power of detergents to wipe out bacteria
• T-cell ‘training grounds’ behind robust immune system response seen in adenovirus vaccines
• New spray could someday help heal damage after a heart attack
• Signaling molecule may help prevent Alzheimer’s disease
• Fungi that live in the gut influence health and disease
• Like priming a pump, cells damaged by chronic lung disease can result in severe COVID
• ‘Clock’ created to predict immunological health and chronic diseases of aging
• A fermented-food diet increases microbiome diversity and lowers inflammation, study finds
• Progress towards new treatments for tuberculosis
• Sensing ‘junk’ RNA after chemotherapy enhances blood regeneration
• Scientists blueprint bacterial enzyme believed to ‘stealthily’ suppress immune response
• Anti-tumor agent from the intestine
• Biomaterial vaccines ward off broad range of bacterial infections and septic shock
• Potential marker for success of immunotherapy in the treatment of lung cancer
• Discovery shows how tuning the immune system may enhance vaccines and ease disease
• How Ebola virus manages to evade the body’s immune defenses
• Study reveals how our immune system reacts to COVID-19 variants
• Scientists closing in on map of the mammalian immune system
• Engineered cells successfully treat cardiovascular and pulmonary disease
• New cancer findings can give wider access to immunotherapy
• Structures discovered in brain cancer patients can help fight tumors
• Being clean and hygienic need not impair childhood immunity
• Study ties milder COVID-19 symptoms to prior run-ins with other coronaviruses
• Study finds 94 percent of patients with cancer respond well to COVID-19 vaccines
• How a COVID-19 infection changes blood cells in the long run
• Researchers discover unique ‘spider web’ mechanism that traps, kills viruses
• COVID-19 vaccine generates immune structures critical for lasting immunity
• Connective tissue protein fights bacterial infection
• Researchers engineer cells to destroy malignant tumor cells but leave the rest alone
• Muscling up with nanoparticle-based anti-inflammatory therapy
• How immune cells can be trained to fight infections

Autoimmune Disease News

• New approach may lead to better diagnostic techniques for autoimmune disorders
• New Oral Drug Found to Reduce Relapses in Multiple Sclerosis Patients.  A new oral drug–teriflunomide–has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. ScienceDaily (Oct. 7, 2011)
• New oral drug found to reduce relapses in multiple sclerosis patients. A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. Science Daily (Oct 6, 2011)
• Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases. Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. Cleveland Clinic. (Oct. 7, 2011)
• Autoimmune diseases a growing problem, Johns Hopkins expert says. Autoimmune diseases are a large and growing problem, particularly in the Caribbean and the United States, says Dr. Noel Rose, director, Center for Autoimmune Disease Research at John Hopkins University, who presented on Autoimmune Disease: The Common Thread, during the Caribbean Autoimmune Diseases Summit 2011. Trinidad Guardian. (Oct. 4, 2011)
• New Research Could Extend Life of Arthritic Joints. A medication already approved to build bone mass in patients with osteoporosis–human parathyroid hormone (brand name: Forteo)–also builds cartilage around joints and could potentially be re-purposed to treat millions of people suffering from arthritis, according to orthopaedic research at the University of Rochester Medical Center. ScienceDaily (Sep. 21, 2011)
• Components That Keep Immune System in Check Identified.  Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body’s own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.  Now, researchers at the University of North Carolina at Chapel Hill have revealed the genetic underpinnings of the cells that can prevent the immune response from turning cannibalistic. Their finding lends insight into these key cells, which are currently being tested as treatments for autoimmune diseases such as type I diabetes, arthritis and lupus. ScienceDaily (Sep. 19, 2011)
• Blocking Inflammation Could Lead to Tailored Medical Treatments.  Researchers at the University of Calgary have discovered a new class of molecules that can inhibit   inflammation in the body – a key feature in autoimmune disease. Current anti-inflammatory drugs block all inflammation in the body. However, these newly discovered molecules may offer a more tailored course of treatment for some diseases, for example to help people suffering from inflammatory diseases such as Inflammatory Bowel Disease (IBD). ScienceDaily (Sep. 19, 2011)
• Starving inflammatory immune cells slows damage caused by multiple sclerosis, study finds.  Researchers report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis (MS).  Science Daily. (Sep 1,  2011)
• University of Miami Researchers Target Inflammatory and Autoimmune Diseases.  New research shows that activating a specific integrin—one of the receptors that mediate attachment between a cell and surrounding tissue and play a role in cell signaling—could lead to more therapies for fighting inflammatory and autoimmune diseases that afflict millions of people worldwide–Miller School of Medicine (Sept. 12, 2011)
• New Anti-Inflammatory Agents Silence Overactive Immune Response; offer  a promising new approach to treat inflammatory auto-immune disorders such as lupus and multiple sclerosis–Science Daily (Aug. 16, 2011)
• Three artists Shine Celebrity Spotlight on Autoimmune Disease Family Ties. Autoimmune disease often runs in families. Three celebrities recently announced their own fight with autoimmune disease and the family connections. American Autoimmune Related Diseases Association (AARDA). (July 28, 2100)
• Anti-malaria drug chloroquine finding may lead to treatments for arthritis, cancer and other diseases. In a new study, scientists demonstrate on the molecular level how the anti-malaria drug chloroquine (widely used to control inflammation in autoimmune diseases such as APS)  represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis and certain cancers – Science Daily (July 18, 2011)

• Newly Discovered B Cells Suggest Why Women Suffer More Autoimmune Disease  – National Jewish Hospital (July 1, 2011)

• Shingles can increase risk of triggering multiple sclerosis, study finds – Los Angeles Times (June 9, 2011)

• New approach for identifying autoimmune diseases developed by Harvard Researchers – Science Daily (June 2, 2011)

• Cardiac Arrhythmia Tied to Autoimmune Diseases – Doctors Lounge (May 6, 2011)

• Lupus complication rates soar in young people – Medical News Today (March 29, 2011)