Recent Autoimmune System News from Science Daily:

 

• Discoveries made in how immune system detects hidden intruders
• T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity
• Injectable hydrogel could someday lead to more effective vaccines
• Study connects hormones we’re born with to lifetime risk for immunological diseases
• Key role of immune cells in brain infection
• Human white blood cells use molecular paddles to swim
• Certain immunosuppressive drugs do not increase risk for COVID-19, study finds
• Immune system affects mind and body, study indicates
• Excessive lung release of neutrophil DNA traps may explain severe complications in COVID-19 patients
• New immunotherapy to beat cancer
• Antibiotic molecule enables immune system to kill HIV infected cells
• Safeguarding of key DNA sensor in innate immune system
• Scientists decipher role of a stress response gene
• Allergic immune responses help fight bacterial infections
• Cell-autonomous immunity shaped human evolution
• Delayed immune responses may drive COVID-19 mortality rates among men and the elderly
• Cellular-level interactions that lead to the cytokine storm in COVID-19
• COVID-19 high-risk groups: Why the immune system is less effective at fighting the virus
• Recommendations measuring persistent HIV reservoirs
• Unconventional T cells in severe COVID-19 patients could predict disease outcome
• Does the COVID-19 cytokine storm exist?
• How to capture images of cells at work inside our lungs
• Obesity may alter immune system response to COVID-19
• Tiny biological package gets drug right to the ‘heart’ of transplant rejection
• Effective cancer immunotherapy further linked to regulating a cell ‘suicide’ gene
• New treatment for drug-resistant bacterial infections
• Scientists use two powerful immunotherapies to eradicate solid tumors
• Inflammation linked to Alzheimer’s disease development
• Possible blood-clotting mechanism in COVID-19 found
• Finding cortisone alternatives with fewer side effects
• Subtypes and developmental pathways of innate T cells identified
• Severe COVID-19 despite or even due to the strong immunity
• RethiNKing which immune cells are the best weapon against lung cancer
• Unique antibody profile sets gluten sensitivity apart from Celiac disease
• Insight on how to build a better flu vaccine
• Microgel immuno-acceptance method could improve pancreatic islet transplant success
• Strokes in babies are surprisingly common; here’s how the body rushes to the rescue
• Antibody blockade effective in treatment of severe COVID-19
• Giant nanomachine aids the immune system
• Beating HIV and COVID-19 may depend on tweaking vaccine molecules
• Prior Zika virus infection increases risk of severe dengue disease
• Duchenne: ‘Crosstalk’ between muscle and spleen
• Researchers identify RNA molecule that helps lung cancer cells evade immune system
• New tool identifies which cancer patients are most likely to benefit from immunotherapy
• Unique HIV reservoirs in elite controllers
• Flexible targets help immune system make finely-tuned antibodies
• Reprogramming immune cells to reduce inflammation, promote tissue repair
• Inflammatory bowel disease linked to an immune cell run amok
• In one cancer therapy, two halves are safer than a whole
• Finding a way to STING tumor growth

Autoimmune Disease News

• New approach may lead to better diagnostic techniques for autoimmune disorders
• New Oral Drug Found to Reduce Relapses in Multiple Sclerosis Patients.  A new oral drug–teriflunomide–has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. ScienceDaily (Oct. 7, 2011)
• New oral drug found to reduce relapses in multiple sclerosis patients. A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. Science Daily (Oct 6, 2011)
• Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases. Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. Cleveland Clinic. (Oct. 7, 2011)
• Autoimmune diseases a growing problem, Johns Hopkins expert says. Autoimmune diseases are a large and growing problem, particularly in the Caribbean and the United States, says Dr. Noel Rose, director, Center for Autoimmune Disease Research at John Hopkins University, who presented on Autoimmune Disease: The Common Thread, during the Caribbean Autoimmune Diseases Summit 2011. Trinidad Guardian. (Oct. 4, 2011)
• New Research Could Extend Life of Arthritic Joints. A medication already approved to build bone mass in patients with osteoporosis–human parathyroid hormone (brand name: Forteo)–also builds cartilage around joints and could potentially be re-purposed to treat millions of people suffering from arthritis, according to orthopaedic research at the University of Rochester Medical Center. ScienceDaily (Sep. 21, 2011)
• Components That Keep Immune System in Check Identified.  Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body’s own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.  Now, researchers at the University of North Carolina at Chapel Hill have revealed the genetic underpinnings of the cells that can prevent the immune response from turning cannibalistic. Their finding lends insight into these key cells, which are currently being tested as treatments for autoimmune diseases such as type I diabetes, arthritis and lupus. ScienceDaily (Sep. 19, 2011)
• Blocking Inflammation Could Lead to Tailored Medical Treatments.  Researchers at the University of Calgary have discovered a new class of molecules that can inhibit   inflammation in the body – a key feature in autoimmune disease. Current anti-inflammatory drugs block all inflammation in the body. However, these newly discovered molecules may offer a more tailored course of treatment for some diseases, for example to help people suffering from inflammatory diseases such as Inflammatory Bowel Disease (IBD). ScienceDaily (Sep. 19, 2011)
• Starving inflammatory immune cells slows damage caused by multiple sclerosis, study finds.  Researchers report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis (MS).  Science Daily. (Sep 1,  2011)
• University of Miami Researchers Target Inflammatory and Autoimmune Diseases.  New research shows that activating a specific integrin—one of the receptors that mediate attachment between a cell and surrounding tissue and play a role in cell signaling—could lead to more therapies for fighting inflammatory and autoimmune diseases that afflict millions of people worldwide–Miller School of Medicine (Sept. 12, 2011)
• New Anti-Inflammatory Agents Silence Overactive Immune Response; offer  a promising new approach to treat inflammatory auto-immune disorders such as lupus and multiple sclerosis–Science Daily (Aug. 16, 2011)
• Three artists Shine Celebrity Spotlight on Autoimmune Disease Family Ties. Autoimmune disease often runs in families. Three celebrities recently announced their own fight with autoimmune disease and the family connections. American Autoimmune Related Diseases Association (AARDA). (July 28, 2100)
• Anti-malaria drug chloroquine finding may lead to treatments for arthritis, cancer and other diseases. In a new study, scientists demonstrate on the molecular level how the anti-malaria drug chloroquine (widely used to control inflammation in autoimmune diseases such as APS)  represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis and certain cancers – Science Daily (July 18, 2011)

• Newly Discovered B Cells Suggest Why Women Suffer More Autoimmune Disease  – National Jewish Hospital (July 1, 2011)

• Shingles can increase risk of triggering multiple sclerosis, study finds – Los Angeles Times (June 9, 2011)

• New approach for identifying autoimmune diseases developed by Harvard Researchers – Science Daily (June 2, 2011)

• Cardiac Arrhythmia Tied to Autoimmune Diseases – Doctors Lounge (May 6, 2011)

• Lupus complication rates soar in young people – Medical News Today (March 29, 2011)