Recent Autoimmune System News from Science Daily:

 

• Why do some neurons degenerate and die in Alzheimer’s disease, but not others?
• Skin and immune cells coordinate defenses against assault
• Defective epithelial barriers linked to two billion chronic diseases
• Crohn’s disease patients have specific IgG antibodies to human bacterial flagellins
• Our immune systems blanket the SARS-CoV-2 spike protein with antibodies
• Microneedles are promising devices for painless drug delivery with minimal side effects
• Tracking down the tiniest of forces: How T cells detect invaders
• Restricting growth, spread of head and neck cancers
• A trait of the rare few whose bodies naturally control HIV: ‘trained’ immune cells
• Researchers identify protein ‘signature’ of severe COVID-19
• Intranasal influenza vaccine enhances immune response and offers broad protection
• Engineering T cells to attack cancer broadly
• Shortage of DNA building blocks in the cell releases mitochondrial DNA
• Prior SARS-CoV-2 infection boosts response to variants after first vaccine dose
• New atlas of genetic function maps complexities of immune system and immune diseases
• How meningitis-causing bacteria may sense fever to avoid immune killing
• How SARS-CoV-2 hijacks human cells to evade immune system
• New, rapid CRISPR/Cas9 method identifies key genes in zebrafish spinal cord regeneration
• Treating severe COVID-19 cases
• SARS-CoV-2 curtails immune response in the gut
• Common inflammatory bowel disease treatment blunts COVID-19 vaccine response, study finds
• Newly discovered immune cell function vital to healing
• Bacteria and viruses infect our cells through sugars: Now researchers want to know how they do it
• Immune system, not COVID virus, may pose greatest risk to pregnant women
• A new method for fighting ‘cold’ tumors
• Fighting harmful bacteria with nanoparticles
• Artificial intelligence model predicts which key of the immune system opens the locks of coronavirus
• SARS-CoV-2: Infection induces antibodies capable of killing infected cells regardless of disease severity
• Shift-work causes negative impacts on health, affects men and women differently
• New insights on inflammation in COVID-19
• The immune link between a leaky blood-brain barrier and schizophrenia
• Differing immune responses discovered in asymptomatic cases vs those with severe COVID-19
• Organ tissues become increasingly immune throughout life
• Overgrowth of gut yeast in newborns may increase asthma risk
• B cell activating factor possible key to hemophilia immune tolerance
• Microglia, Stockholm syndrome and miraculous cures in glioblastoma patients
• Those who had COVID-19 may only need one vaccine dose, study suggests
• New ‘time machine’ technique to measure cells
• Self-assembling nanofibers prevent damage from inflammation
• New discovery could lead to therapies for patients with Duchenne muscular dystrophy
• A mother’s fat intake can impact infant infectious disease outcomes
• Study reveals cancer immunotherapy patients at most risk of life-threatening side effects
• Study reveals crucial details on skin-related side effects of cancer immune therapies
• Personalized cancer vaccine deemed safe, shows potential benefit against cancer
• Interleukin-33 involved in immunity to Sars-CoV-2
• COVID-19 causes ‘unexpected’ cellular response in the lungs, research finds
• STING gene methylation allows melanoma to evade the immune system
• First images of cells exposed to COVID-19 vaccine reveal native-like coronavirus spikes
• Software package enables deeper understanding of cancer immune responses
• Replacing what was lost: A novel cell therapy for type I diabetes mellitus

Autoimmune Disease News

• New approach may lead to better diagnostic techniques for autoimmune disorders
• New Oral Drug Found to Reduce Relapses in Multiple Sclerosis Patients.  A new oral drug–teriflunomide–has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. ScienceDaily (Oct. 7, 2011)
• New oral drug found to reduce relapses in multiple sclerosis patients. A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. Science Daily (Oct 6, 2011)
• Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases. Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. Cleveland Clinic. (Oct. 7, 2011)
• Autoimmune diseases a growing problem, Johns Hopkins expert says. Autoimmune diseases are a large and growing problem, particularly in the Caribbean and the United States, says Dr. Noel Rose, director, Center for Autoimmune Disease Research at John Hopkins University, who presented on Autoimmune Disease: The Common Thread, during the Caribbean Autoimmune Diseases Summit 2011. Trinidad Guardian. (Oct. 4, 2011)
• New Research Could Extend Life of Arthritic Joints. A medication already approved to build bone mass in patients with osteoporosis–human parathyroid hormone (brand name: Forteo)–also builds cartilage around joints and could potentially be re-purposed to treat millions of people suffering from arthritis, according to orthopaedic research at the University of Rochester Medical Center. ScienceDaily (Sep. 21, 2011)
• Components That Keep Immune System in Check Identified.  Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body’s own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.  Now, researchers at the University of North Carolina at Chapel Hill have revealed the genetic underpinnings of the cells that can prevent the immune response from turning cannibalistic. Their finding lends insight into these key cells, which are currently being tested as treatments for autoimmune diseases such as type I diabetes, arthritis and lupus. ScienceDaily (Sep. 19, 2011)
• Blocking Inflammation Could Lead to Tailored Medical Treatments.  Researchers at the University of Calgary have discovered a new class of molecules that can inhibit   inflammation in the body – a key feature in autoimmune disease. Current anti-inflammatory drugs block all inflammation in the body. However, these newly discovered molecules may offer a more tailored course of treatment for some diseases, for example to help people suffering from inflammatory diseases such as Inflammatory Bowel Disease (IBD). ScienceDaily (Sep. 19, 2011)
• Starving inflammatory immune cells slows damage caused by multiple sclerosis, study finds.  Researchers report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis (MS).  Science Daily. (Sep 1,  2011)
• University of Miami Researchers Target Inflammatory and Autoimmune Diseases.  New research shows that activating a specific integrin—one of the receptors that mediate attachment between a cell and surrounding tissue and play a role in cell signaling—could lead to more therapies for fighting inflammatory and autoimmune diseases that afflict millions of people worldwide–Miller School of Medicine (Sept. 12, 2011)
• New Anti-Inflammatory Agents Silence Overactive Immune Response; offer  a promising new approach to treat inflammatory auto-immune disorders such as lupus and multiple sclerosis–Science Daily (Aug. 16, 2011)
• Three artists Shine Celebrity Spotlight on Autoimmune Disease Family Ties. Autoimmune disease often runs in families. Three celebrities recently announced their own fight with autoimmune disease and the family connections. American Autoimmune Related Diseases Association (AARDA). (July 28, 2100)
• Anti-malaria drug chloroquine finding may lead to treatments for arthritis, cancer and other diseases. In a new study, scientists demonstrate on the molecular level how the anti-malaria drug chloroquine (widely used to control inflammation in autoimmune diseases such as APS)  represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis and certain cancers – Science Daily (July 18, 2011)

• Newly Discovered B Cells Suggest Why Women Suffer More Autoimmune Disease  – National Jewish Hospital (July 1, 2011)

• Shingles can increase risk of triggering multiple sclerosis, study finds – Los Angeles Times (June 9, 2011)

• New approach for identifying autoimmune diseases developed by Harvard Researchers – Science Daily (June 2, 2011)

• Cardiac Arrhythmia Tied to Autoimmune Diseases – Doctors Lounge (May 6, 2011)

• Lupus complication rates soar in young people – Medical News Today (March 29, 2011)