Recent Autoimmune System News from Science Daily:

 

• Promising path towards developing flu treatment using lipid target
• Potential breakthrough in understanding tumor dormancy
• Dead cells disrupt how immune cells respond to wounds and patrol for infection
• Certain placental stem cells can regenerate heart after heart attack
• Scientists capture first-ever video of body’s safety test for T-cells
• Being sick in the morning can be different from being sick at night
• New findings could lead to improved vaccinations against sexually transmitted infections
• How host-cell enzymes combat the coronavirus
• Antibody responses vs. Ebola keep evolving in survivors, months after recovery
• Antibiotic treatment alleviates Alzheimer’s disease symptoms in male mice
• Genomic collision may explain why many kidney transplants fail
• New strategy of reprogramming regulatory T cells may improve cancer therapies
• Researchers block protein that plays a key role in Alzheimer’s disease
• On the way to fighting staph infections with the body’s immune system
• Immune system discovery could aid quest for stem cell therapies
• Plaque in arteries may not all be the same; targeting specific immune cells in plaque may reduce heart attack and stroke risk
• Probiotic-derived molecule may suppress fatal brain inflammation, preclinical study finds
• Flu virus’ best friend: Low humidity
• Why Hodgkin’s lymphoma cells grow uncontrollably
• Some biologic treatments for psoriasis may be safer for patients
• A link between mitochondrial damage and osteoporosis
• New HIV vaccine strategy ‘pumps’ the immune system
• Challenging metabolism may help fight disease
• Groundbreaking study could lead to fast, simple test for Ebola virus
• Tumor mutations may predict response to immunotherapy
• Vaccine design can dramatically improve cancer immunotherapies
• Drug candidate for reversing mucosal barrier damage by HIV
• Pushing early beta-cell proliferation can halt autoimmune attack in type 1 diabetes model
• New immunodeficiency disease discovered
• How the immune system recognizes pathogens: Interaction Time
• Viral peptides critical to natural HIV control
• Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy
• Researchers ready B cells for novel cell therapy
• New target to improve response to cancer immunotherapy
• Atherosclerosis: Induced cell death destabilizes plaques
• Drug can reverse hyperactivity induced by parasitic infection
• Research decodes one way cancer survives treatment, proposes a way to prevent it
• Biomarker for chronic fatigue syndrome
• Susceptibility to disease develops during childhood
• TET proteins regulate factors essential for normal antibody production
• Humanization of antibodies targeting human herpesvirus 6B
• Study in mice uncovers an unknown pathway for breast cancer tumors to recur
• Fishing for cures: New zebrafish model identifies drugs that kill pediatric cancer cells
• Dermcidin may play role in the pathogenesis of skin disease hidradenitis suppurativa
• BRAF protein modification could slow tumor growth
• Elderberry compounds could help minimize flu symptoms, study suggests
• Rare disease gives new insight into regulatory T cell function
• Revealed: The secret superpower that makes C. difficile so deadly
• RNA sequencing used to discover novel genes and pathways in celiac disease
• Vitamin D study sheds light on immune system effects

Autoimmune Disease News

• New approach may lead to better diagnostic techniques for autoimmune disorders
• New Oral Drug Found to Reduce Relapses in Multiple Sclerosis Patients.  A new oral drug–teriflunomide–has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. ScienceDaily (Oct. 7, 2011)
• New oral drug found to reduce relapses in multiple sclerosis patients. A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. Science Daily (Oct 6, 2011)
• Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases. Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. Cleveland Clinic. (Oct. 7, 2011)
• Autoimmune diseases a growing problem, Johns Hopkins expert says. Autoimmune diseases are a large and growing problem, particularly in the Caribbean and the United States, says Dr. Noel Rose, director, Center for Autoimmune Disease Research at John Hopkins University, who presented on Autoimmune Disease: The Common Thread, during the Caribbean Autoimmune Diseases Summit 2011. Trinidad Guardian. (Oct. 4, 2011)
• New Research Could Extend Life of Arthritic Joints. A medication already approved to build bone mass in patients with osteoporosis–human parathyroid hormone (brand name: Forteo)–also builds cartilage around joints and could potentially be re-purposed to treat millions of people suffering from arthritis, according to orthopaedic research at the University of Rochester Medical Center. ScienceDaily (Sep. 21, 2011)
• Components That Keep Immune System in Check Identified.  Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body’s own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.  Now, researchers at the University of North Carolina at Chapel Hill have revealed the genetic underpinnings of the cells that can prevent the immune response from turning cannibalistic. Their finding lends insight into these key cells, which are currently being tested as treatments for autoimmune diseases such as type I diabetes, arthritis and lupus. ScienceDaily (Sep. 19, 2011)
• Blocking Inflammation Could Lead to Tailored Medical Treatments.  Researchers at the University of Calgary have discovered a new class of molecules that can inhibit   inflammation in the body – a key feature in autoimmune disease. Current anti-inflammatory drugs block all inflammation in the body. However, these newly discovered molecules may offer a more tailored course of treatment for some diseases, for example to help people suffering from inflammatory diseases such as Inflammatory Bowel Disease (IBD). ScienceDaily (Sep. 19, 2011)
• Starving inflammatory immune cells slows damage caused by multiple sclerosis, study finds.  Researchers report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis (MS).  Science Daily. (Sep 1,  2011)
• University of Miami Researchers Target Inflammatory and Autoimmune Diseases.  New research shows that activating a specific integrin—one of the receptors that mediate attachment between a cell and surrounding tissue and play a role in cell signaling—could lead to more therapies for fighting inflammatory and autoimmune diseases that afflict millions of people worldwide–Miller School of Medicine (Sept. 12, 2011)
• New Anti-Inflammatory Agents Silence Overactive Immune Response; offer  a promising new approach to treat inflammatory auto-immune disorders such as lupus and multiple sclerosis–Science Daily (Aug. 16, 2011)
• Three artists Shine Celebrity Spotlight on Autoimmune Disease Family Ties. Autoimmune disease often runs in families. Three celebrities recently announced their own fight with autoimmune disease and the family connections. American Autoimmune Related Diseases Association (AARDA). (July 28, 2100)
• Anti-malaria drug chloroquine finding may lead to treatments for arthritis, cancer and other diseases. In a new study, scientists demonstrate on the molecular level how the anti-malaria drug chloroquine (widely used to control inflammation in autoimmune diseases such as APS)  represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis and certain cancers – Science Daily (July 18, 2011)

• Newly Discovered B Cells Suggest Why Women Suffer More Autoimmune Disease  – National Jewish Hospital (July 1, 2011)

• Shingles can increase risk of triggering multiple sclerosis, study finds – Los Angeles Times (June 9, 2011)

• New approach for identifying autoimmune diseases developed by Harvard Researchers – Science Daily (June 2, 2011)

• Cardiac Arrhythmia Tied to Autoimmune Diseases – Doctors Lounge (May 6, 2011)

• Lupus complication rates soar in young people – Medical News Today (March 29, 2011)