Recent Autoimmune System News from Science Daily:

 

• Boosting stem cell activity can enhance immunotherapy benefits
• Altered ‘coat’ disguises fatal brain virus from neutralizing antibodies
• How tissue geometry influences the movement of cells through the body
• Engineered immune cells elicit broad response to HIV in mice, offering hope for vaccine
• Stem cell transplantation: Undesirable rejection mechanism identified
• In the lab, scientists identify possible COVID-19 treatment
• Brain protein could be starting point for new treatments for pancreatic cancer
• Coinfection: More than the sum of its parts
• Diabetes, hypertension may increase risk of COVID-19 brain complications
• Kids mount a COVID-19 immune response without detection of the SARSCoV-2 virus, case study finds
• Study reveals how smoking worsens COVID-19 infection in the airways
• Chronic alcohol use reshapes the brain’s immune landscape, driving anxiety and addiction
• Parasite infection discovery could assist mental health treatments
• Parasitic worms offer ‘the missing link’ on the dual nature of a key immune regulator
• Antibody evolution may predict COVID-19 outcomes
• Promising MS drug may worsen disease
• Dissecting the immune characteristics of severe COVID-19 responses
• Link between Alzheimer’s disease and gut microbiota is confirmed
• Mimicking SARS-CoV-2 nasal infection in monkeys
• Scientists pinpoint two new potential therapeutic targets for rheumatoid arthritis
• New study points to a better way to ward off asthma triggers
• Scientists identify protein that protects against Lyme
• Uracil switch in SARS-CoV-2 genome alters innate immune responses
• Vitamin C’s effectiveness against COVID-19 may hinge on vitamin’s natural transporter levels
• Glioblastoma nanomedicine crosses into brain in mice, eradicates recurring brain cancer
• A viable vaccine for tough tumors
• ‘Goldilocks’ neonatal immune response may protect against autism
• Tracking down the causes of heart attack
• Personalized cancer vaccine clinical trial to expand following promising early results
• Genetic disposition protects immune system from aging
• The natural artistry of disease: A wintry landscape in the eye
• Pre-existing coronavirus antibodies could help protect children against new pandemic strain
• Mystery molecule in bacteria is revealed to be a guard
• Children produce different antibodies in response to SARS-CoV-2
• Scientists make breakthrough discovery of new therapeutic targets for Alzheimer’s
• Researchers identify key marker to help speed development of CMV vaccines
• Why protecting the brain against infection takes guts
• Study uncovers subset of COVID-19 patients who recover quickly and sustain antibodies
• Some of the principal treatments for osteoporosis could reduce the incidence of COVID-19, study finds
• How the immune system remembers viruses
• Seven different ‘disease forms’ identified in mild COVID-19
• Malaria parasites adapt to survive the dry season
• How allergens trigger itching: Finding points to new targets for allergy drug development
• How the immune system deals with the gut’s plethora of microbes
• Priming the immune system to attack cancer
• Over 80 percent of COVID-19 patients have vitamin D deficiency, study finds
• New map of the immune landscape in pancreatic cancer could guide immunotherapy
• Can scientists take the STING out of common respiratory viruses?
• T-cells from recovered COVID-19 patients show promise to protect vulnerable patients from infection
• PTSD and alcohol abuse go hand-in-hand, but males and females exhibit symptoms differently

Autoimmune Disease News

• New approach may lead to better diagnostic techniques for autoimmune disorders
• New Oral Drug Found to Reduce Relapses in Multiple Sclerosis Patients.  A new oral drug–teriflunomide–has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. ScienceDaily (Oct. 7, 2011)
• New oral drug found to reduce relapses in multiple sclerosis patients. A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. Science Daily (Oct 6, 2011)
• Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases. Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. Cleveland Clinic. (Oct. 7, 2011)
• Autoimmune diseases a growing problem, Johns Hopkins expert says. Autoimmune diseases are a large and growing problem, particularly in the Caribbean and the United States, says Dr. Noel Rose, director, Center for Autoimmune Disease Research at John Hopkins University, who presented on Autoimmune Disease: The Common Thread, during the Caribbean Autoimmune Diseases Summit 2011. Trinidad Guardian. (Oct. 4, 2011)
• New Research Could Extend Life of Arthritic Joints. A medication already approved to build bone mass in patients with osteoporosis–human parathyroid hormone (brand name: Forteo)–also builds cartilage around joints and could potentially be re-purposed to treat millions of people suffering from arthritis, according to orthopaedic research at the University of Rochester Medical Center. ScienceDaily (Sep. 21, 2011)
• Components That Keep Immune System in Check Identified.  Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body’s own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.  Now, researchers at the University of North Carolina at Chapel Hill have revealed the genetic underpinnings of the cells that can prevent the immune response from turning cannibalistic. Their finding lends insight into these key cells, which are currently being tested as treatments for autoimmune diseases such as type I diabetes, arthritis and lupus. ScienceDaily (Sep. 19, 2011)
• Blocking Inflammation Could Lead to Tailored Medical Treatments.  Researchers at the University of Calgary have discovered a new class of molecules that can inhibit   inflammation in the body – a key feature in autoimmune disease. Current anti-inflammatory drugs block all inflammation in the body. However, these newly discovered molecules may offer a more tailored course of treatment for some diseases, for example to help people suffering from inflammatory diseases such as Inflammatory Bowel Disease (IBD). ScienceDaily (Sep. 19, 2011)
• Starving inflammatory immune cells slows damage caused by multiple sclerosis, study finds.  Researchers report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis (MS).  Science Daily. (Sep 1,  2011)
• University of Miami Researchers Target Inflammatory and Autoimmune Diseases.  New research shows that activating a specific integrin—one of the receptors that mediate attachment between a cell and surrounding tissue and play a role in cell signaling—could lead to more therapies for fighting inflammatory and autoimmune diseases that afflict millions of people worldwide–Miller School of Medicine (Sept. 12, 2011)
• New Anti-Inflammatory Agents Silence Overactive Immune Response; offer  a promising new approach to treat inflammatory auto-immune disorders such as lupus and multiple sclerosis–Science Daily (Aug. 16, 2011)
• Three artists Shine Celebrity Spotlight on Autoimmune Disease Family Ties. Autoimmune disease often runs in families. Three celebrities recently announced their own fight with autoimmune disease and the family connections. American Autoimmune Related Diseases Association (AARDA). (July 28, 2100)
• Anti-malaria drug chloroquine finding may lead to treatments for arthritis, cancer and other diseases. In a new study, scientists demonstrate on the molecular level how the anti-malaria drug chloroquine (widely used to control inflammation in autoimmune diseases such as APS)  represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis and certain cancers – Science Daily (July 18, 2011)

• Newly Discovered B Cells Suggest Why Women Suffer More Autoimmune Disease  – National Jewish Hospital (July 1, 2011)

• Shingles can increase risk of triggering multiple sclerosis, study finds – Los Angeles Times (June 9, 2011)

• New approach for identifying autoimmune diseases developed by Harvard Researchers – Science Daily (June 2, 2011)

• Cardiac Arrhythmia Tied to Autoimmune Diseases – Doctors Lounge (May 6, 2011)

• Lupus complication rates soar in young people – Medical News Today (March 29, 2011)