Recent Autoimmune System News from Science Daily:

 

• The architecture of a ‘shape-shifting’ norovirus
• Cells must age for muscles to regenerate in muscle-degenerating diseases
• Novel cell-based cancer immunotherapy shows promise in early studies
• Study helps to identify medications which are safe to use in treatment of COVID-19
• ‘Living drug factories’ might treat diabetes and other diseases
• Potential boost to immunotherapy
• Advances in production of retinal cells for treating blindness
• How to boost immune response to vaccines in older people
• Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
• Experiments in mice and human cells shed light on best way to deliver nanoparticle therapy for cancer
• Too much salt weakens the immune system
• Ultrafast repeated staining and destaining of cell samples for tumor diagnostics
• Brake on immune activity identified, raising new possibilities for anticancer therapy
• How tissues harm themselves during wound healing
• Antibodies in the brain trigger epilepsy
• CAR macrophages go beyond T cells to fight solid tumors
• Immunotherapy using ‘young cells’ offers promising option against cancer
• Using ‘organs-on-a-chip’ to model complicated diseases
• Alzheimer’s disease: Inflammation triggers fatal cycle
• ‘Natural killer’ cells could halt Parkinson’s progression
• New understanding of immune modulator interleukin-2 guides drug discovery
• COVID-19: The immune system can fight back
• Immunotherapy combo achieves reservoir shrinkage in HIV model
• New strategy for the management of inflammatory pain
• Mimicking cancer’s evasive tactics, microparticles show promise for transplant rejection
• Blood stem cells boost immunity by keeping a record of previous infections
• Scientists identify potential targets for immune responses to novel coronavirus
• Sensing infection, suppressing regeneration
• Immune cells against Alzheimer’s?
• Babies born prematurely can catch up their immune systems
• The harmful effects of stress during pregnancy can last a lifetime
• Social isolation could cause physical inflammation
• Novel sepsis treatment enhances bacterial capture by neutrophil ‘traps’
• Blocking immune T-cell regulator may help eliminate tumors
• Visceral fat delivers signal to the brain that hurts cognition
• Protein critical for wound healing after spinal cord injury
• Scientists show drug may greatly improve cancer immunotherapy success
• Immunology: Tonsils as a testbed
• The first Cell Atlas for the human Thymus
• Early intervention following traumatic brain injury reduces epilepsy risk
• Study unravels how our immune system deals with fungal and viral infections
• Scientists discover new ‘Jekyll and Hyde’ immune cell
• Nanosize device ‘uncloaks’ cancer cells in mice and reveals them to the immune system
• Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells
• COVID-19 vaccine development
• The effects of obesity mirror those of aging
• Origins of immune system mapped, opening doors for new cancer immunotherapies
• How malaria detects and shields itself from approaching immune cells
• New technology analyses single cancer cells in lab grown tumors
• Rogue cells at root of autoimmune disease

Autoimmune Disease News

• New approach may lead to better diagnostic techniques for autoimmune disorders
• New Oral Drug Found to Reduce Relapses in Multiple Sclerosis Patients.  A new oral drug–teriflunomide–has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. ScienceDaily (Oct. 7, 2011)
• New oral drug found to reduce relapses in multiple sclerosis patients. A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease. Science Daily (Oct 6, 2011)
• Cleveland Clinic study discovers new targets for treating inflammatory, autoimmune diseases. Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. Cleveland Clinic. (Oct. 7, 2011)
• Autoimmune diseases a growing problem, Johns Hopkins expert says. Autoimmune diseases are a large and growing problem, particularly in the Caribbean and the United States, says Dr. Noel Rose, director, Center for Autoimmune Disease Research at John Hopkins University, who presented on Autoimmune Disease: The Common Thread, during the Caribbean Autoimmune Diseases Summit 2011. Trinidad Guardian. (Oct. 4, 2011)
• New Research Could Extend Life of Arthritic Joints. A medication already approved to build bone mass in patients with osteoporosis–human parathyroid hormone (brand name: Forteo)–also builds cartilage around joints and could potentially be re-purposed to treat millions of people suffering from arthritis, according to orthopaedic research at the University of Rochester Medical Center. ScienceDaily (Sep. 21, 2011)
• Components That Keep Immune System in Check Identified.  Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body’s own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease.  Now, researchers at the University of North Carolina at Chapel Hill have revealed the genetic underpinnings of the cells that can prevent the immune response from turning cannibalistic. Their finding lends insight into these key cells, which are currently being tested as treatments for autoimmune diseases such as type I diabetes, arthritis and lupus. ScienceDaily (Sep. 19, 2011)
• Blocking Inflammation Could Lead to Tailored Medical Treatments.  Researchers at the University of Calgary have discovered a new class of molecules that can inhibit   inflammation in the body – a key feature in autoimmune disease. Current anti-inflammatory drugs block all inflammation in the body. However, these newly discovered molecules may offer a more tailored course of treatment for some diseases, for example to help people suffering from inflammatory diseases such as Inflammatory Bowel Disease (IBD). ScienceDaily (Sep. 19, 2011)
• Starving inflammatory immune cells slows damage caused by multiple sclerosis, study finds.  Researchers report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis (MS).  Science Daily. (Sep 1,  2011)
• University of Miami Researchers Target Inflammatory and Autoimmune Diseases.  New research shows that activating a specific integrin—one of the receptors that mediate attachment between a cell and surrounding tissue and play a role in cell signaling—could lead to more therapies for fighting inflammatory and autoimmune diseases that afflict millions of people worldwide–Miller School of Medicine (Sept. 12, 2011)
• New Anti-Inflammatory Agents Silence Overactive Immune Response; offer  a promising new approach to treat inflammatory auto-immune disorders such as lupus and multiple sclerosis–Science Daily (Aug. 16, 2011)
• Three artists Shine Celebrity Spotlight on Autoimmune Disease Family Ties. Autoimmune disease often runs in families. Three celebrities recently announced their own fight with autoimmune disease and the family connections. American Autoimmune Related Diseases Association (AARDA). (July 28, 2100)
• Anti-malaria drug chloroquine finding may lead to treatments for arthritis, cancer and other diseases. In a new study, scientists demonstrate on the molecular level how the anti-malaria drug chloroquine (widely used to control inflammation in autoimmune diseases such as APS)  represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis and certain cancers – Science Daily (July 18, 2011)

• Newly Discovered B Cells Suggest Why Women Suffer More Autoimmune Disease  – National Jewish Hospital (July 1, 2011)

• Shingles can increase risk of triggering multiple sclerosis, study finds – Los Angeles Times (June 9, 2011)

• New approach for identifying autoimmune diseases developed by Harvard Researchers – Science Daily (June 2, 2011)

• Cardiac Arrhythmia Tied to Autoimmune Diseases – Doctors Lounge (May 6, 2011)

• Lupus complication rates soar in young people – Medical News Today (March 29, 2011)